JASCO will be exhibiting its supercritical fluid chromatography system at the 1st International Conference on SFC to be held on September 23 – 25, 2007 at the Sheraton Station Square Hotel in Pittsburgh, PA.
The two day conference will offer both an exhibition and a scientific program, including vendor workshops and poster presentations. There will be numerous discussions on recent developments in SFC technology as well as new applications.
JASCO will present a poster session on Sunday, September 23, from 6:30 – 7:30 pm, Advantages of Circular Dichroism (CD) Detection for the Determination of Fractionation Timing in Preparative Supercritical Fluid Chromatography (Prep-SFC) for Chiral Separations, presented by Takeshi Kanomata. In addition, JASCO will host a vendor workshop on Monday, September 23, from 12:45 - 1:10 pm, Chiral Separation by Preparative Supercritical Fluid Chromatography using a Circular Dichroism Detector, presented by Craig Silverman.
In 2008, JASCO celebrates its 50th anniversary as a manufacturer of high-quality analytical instruments, which includes both spectroscopy and chromatography products. JASCO boasts a full line of SFC/SFE systems incorporating a unique, patented, back-pressure regulator. The JASCO line includes analytical, semi-preparative and preparative scale systems, as well as supercritical fluid extraction systems. JASCO is the only manufacturer that offers a CD detector that integrates with their HPLC and SFC products.
To receive more information on the 1st International Conference on SFC, go to: www.greenchemistrygroup.org.

JASCO is proud to announce the introduction of the MSV-300 series microspectroscopy system to the U.S. market. This UV/VIS/NIR microspectrophotometer provides transmittance/reflectance measurements of microscopic sample sites for a wide range of wavelengths, from the ultraviolet to the near infrared.
Conventional measurements require samples with dimensions comparable to a mm-sized optical beam. The MSV-300 series can measure color, film thickness, and other spectral properties of a microscopic area for either large or small samples with a minimum spatial resolution of 30 microns. The optional automated X-Y-Z stage provides multi-point or mapping measurements for surface analysis of samples.
The systems feature a wide spectral measurement range, offering continuous measurements between 250 and 2,000 nm (MSV-370) using a spectrometer integrated with a microscopy accessory, the microscope utilizing a PMT detector for the UV-Visible range and a PbS detector for the NIR measurement range. Utilizing dual Cassegrain objective/condenser mirrors, the sample can be easily visualized for transmission or reflection measurements. An integrated CCD camera allows verification of the analysis site and sample position while defining the sample aperture on the software system. All microscope operations are PC-controlled through the Spectra Manager software interface; the CCD video image, virtual instrument interface, sample aperture and reflection/transmission mirror controls which are accessed and controlled through the microscope control software.

The Molecular Chirality Research Organization (MCRO) held its annual Molecular Chirality Symposium on May 15-16 at the Tokyo University of Science in Tokyo, Japan. Since 1999, the organization has presented an award to honor those internationally recognized scientists and companies who have made distinguished contributions in the field of molecular chirality. A beautifully designed bronze sculpture titled “Hand in Art” goes to the recognized recipients. On May 15, this year’s honors went to Professor Hiroshi Tsukube, Osaka City University, and to JASCO.

Approximately 250 people attended the event with special guest lecturers such as Christopher Welch from Merck Research Laboratories in the USA and Josep M. Ribo from the University of Barcelona, Spain. Quite a few other resident scientists participated as well.

The Symposium on Molecular Chirality was initiated by the Pharmaceutical Society of Japan in 1992 to promote progress in the pharmaceutical sciences dealing with chiral drugs. It was held under the auspices of the Chemical Society of Japan and six other Japanese scientific societies. The participation has grown over the years to include a diverse range of disciplines such as organic synthesis, natural products, pharmacology, medicinal chemistry, polymer chemistry, and many others.

The bronze award is a sculpture of a lady’s hand, designed to signify “chirality” a derivation of the Greek word meaning “handedness.” Chirality describes the state of a molecule with isomers that mirror each other. Dr. Shoji Hara, Emeritus Professor at the Tokyo University of Pharmacology and Life Sciences, explained at the meeting that if someone should win the award a second time, a left hand will be sculpted to complete the chirality story, which should encourage people to strive for this achievement again.

JASCO is an analytical instrument manufacturer based in Hachioji, Japan, with offices worldwide. JASCO specializes in the field of spectroscopy and chromatography products, including its world-renowned Circular Dichroism spectrometers, FT-IR, Raman, UV-Vis/NIR, Polarimeters, Fluorescence, HPLC, SFE/SFC, and X-LC™ (High- Performance LC).

JASCO is proud to announce the release of our new Preparative SFE/SFC system. This unit features a versatile modular design and excellent performance.

The heart of the system is JASCO’S patented award-winning back- pressure regulator which allows control of system pressure regardless of solvent composition and flowrate. The pumping system is based on the proven performance of our 1500 series analytical SFE/SFC system and can deliver up to 120ml/min of CO2 and 60 ml/min of modifier and flush solvents at pressures up to 35 MPa (5000 psi). Injections can be manual or fully automated. Repetitive injections can be performed to overlay chromatographic runs. Detection choices include UV and/or CD with MS interface capability.

Fraction collection of up to 8 fractions by time, signal level and/or slope is standard. In addition, spectral purity monitoring of Chiral molecules using the g-factor output of the CD detector is standard with the CD detector option.

Up to 20 mm x 250 mm columns can be accommodated in the column oven while 30mm and larger columns can be used outside the oven.

SF-Nav Process control software is designed for fully automated operation, monitoring and recording of chromatograms, temperatures, and pressures.

JASCO’s Fluorescence detector Model X-LC 3120FP is the industry's only detector for ultra high pressure liquid chromatography (UHPLC) applications. The X-LC 3120FP provides an excellent signal-to-noise ratio with superior stability over a wide wavelength range (220-700 nm) for both excitation and emission. Advanced optics, holographic concave diffraction gratings, and non-spherical mirrors are cleverly incorporated in a compact design resulting in extremely efficient and reliable fluorescence detection.

The X-LC 3120FP is capable of data acquisitions at frequencies up to 50 data points per second to allow for proper detection and integration of narrower peaks associated with UHPLC. The unit’s low dispersion micro flow cell provides excellent peak symmetry by eliminating band-broadening effects to ensure unmatched accuracy and reproducibility. In addition, JASCO's X-LC coupled with the X-LC 3120FP can provide efficiency and speed that was previously not possible in commercial HPLC while maintaining the ability to run traditional HPLC methods including fluorescence detections.

JASCO is proud to introduce the new P-2000 multi-option polarimeter. The P-2000 is designed to be a customizable polarimeter which can be equipped with various options to handle a researcher’s initial requirements and budget; and can also be upgraded in the field at any time as the operator’s requirements change. The P-2000 is a simple unit to operate via PC or hand-held controller - both equipped with Windows software.

The new P-2000 also offers a range of light sources including Tungsten-Halogen, Sodium, or Mercury lamps. Up to two light sources can be simultaneously installed in the instrument giving the P-2000 the widest wavelength range of any polarimeter available; from the UV-Vis region (254 nm) to the NIR region (880 nm). Additionally, sample temperature control is available at (±0.1°C) accuracy.

Inside and out, the new P-2000 polarimeter is in a class by itself. The optimized optical design, 21 CFR 11 compliance, and a lifetime warranty on both its polarizers and modulators make this instrument the clear choice for today’s modern laboratory.