The heart of the system is JASCO’S patented award-winning back-pressure regulator which allows control of system pressure regardless of solvent composition and flowrate. The pumping system is based on the proven performance of our LC-4000 series analytical SFE/SFC system and can deliver up to 120ml/min of CO₂ and 60 ml/min of modifier and flush solvents at pressures up to 35 MPa (5000 psi). Injections can be manual or fully automated. Repetitive injections can be performed to overlay chromatographic runs. Detection choices include UV and/or CD with MS interface capability.

Fraction collection of up to 8 fractions by time, signal level and/or slope is standard. In addition, spectral purity monitoring of Chiral molecules using the g-factor output of the CD detector is standard with the CD detector option.

Up to 20 mm x 250 mm columns can be accommodated in the column oven while 30 mm and larger columns can be used outside the oven.

SF-NAV Process control software is designed for fully automated operation, monitoring and recording of chromatograms, temperatures, and pressures.

• High Throughput
  The low viscosity and high diffusion coefficient of CO₂ make it possible to perform separations and purifications with great efficiency in a short elution time.



• Low cost
  Compared with a preparative HPLC, the total cost can be significantly reduced because of the use of inexpensive CO₂ as mobile phase and the simplicity of sample recovery.



• Safe and Environmentally friendly
  Nonflammable CO₂ is safer than organic solvents. Using CO₂ recovery can offer even less environmental burden.

Specifications

• PU-4380/4386/4387/4388 CO₂ delivery pump
• AS-4350/4358 SFC Autosampler
• BP-4340 Automatic back pressure regulator
• Cyclone separator
• View Cells and Various High Pressure Vessels