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LC-4000 Series Systems

The LC-4000 series offers the broadest range of liquid chromatography instrumentation available from any manufacturer. Proven reliability and excellent sensitivity are combined in systems configured to meet any application. Control is available from panel keypad or JASCO ChromNAV Chromatography Software.

Conventional HPLC and RHPLC Analytical Systems up to 70 MPa

The LC-4000 Series 70 MPa system has been designed to future-proof your HPLC requirements. The LC-4000 70 MPa system can be used with conventional 3 and 5 µm particle size analytical columns at typical lower pressures around 10 to 20 MPa (1500 to 3000 psi) and can also be used with smaller particles such as shorter length UHPLC columns and superficially porous (SPP) or Coreshell that require slightly higher pressure solvent delivery to provide optimum linear velocity through the column.

Isocratic system

This stand-alone system includes a pump, degasser, manual injector and UV/Vis detector. The PU-4180 Pump offers a variable flow rate and memory capacity to store up to 10 files of 64-step programs. The UV-4070/4075 UV/Vis detector provides extremely high sensitivity, spectral scanning and wavelength time-programming. The system can be easily upgraded to full automation as well as elution mode for gradient operations.

Low-pressure gradient system

The LG-4080 low-pressure gradient unit is designed to be used with LC-4000 series pump, enabling up to a 4-solvent quaternary gradient. The PU-4180-LPG is a compact HPLC Quaternary low pressure gradient pump designed to meet the rigorous requirements of wide range of research and routine gradient applications. Built-in low-pressure proportioning valve and degasser enable the highest flexibility in solvent choices and excellent gradient solvent delivery.

UHPLC Analytical Systems at 130 MPa

Ten years after the new segment of the HPLC market, UHPLC has found a niche for those that need to run a large number of samplers or get results quickly. Pioneering column technology is pushing the particle size even smaller. The near 20,000 psi operation of the LC-4000 130 MPa is designed to take advantage of the separation efficiency of the very small particles couple with longer and narrower columns. The LC-4000 130 MPa system incorporates many of the same features as the 70 MPa system, but with materials designed to withstand higher pressures.

High-pressure gradient system

The integrated time programming controls a two-pump binary gradient. By using the JASCO chromatography data system, up to a 3-pump ternary gradient is possible. The MX-4080 is a high pressure dynamic mixer, capable of mixing up to s solvents under high pressure. By changing the chamber capacity, the instrument can be used in various applications.

Preparative HPLC system

The LC-4000 preparative HPLC systems includes three platform options.

  • Up to 20 mL/min for columns up to 21.2 mm I.D.
  • Up to 50 mL/min for columns up to 30 mm I.D.
  • Up to 120 mL/min for columns up to 50 mm I.D.

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